CJC-1295 (no DAC)

Overview

Also known as Mod GRF 1-29, this is the same core GHRH-analog activity as CJC-1295 with DAC, but without the albumin-binding modification. The result is a molecule that is cleared from the body quickly rather than persisting for days.

Proposed Mechanism

Shares the same GHRH receptor activity as CJC-1295 with DAC, but clears quickly rather than binding albumin — producing a GH pulse that more closely resembles natural nocturnal secretion.

Research Context

Because it clears rapidly, research interest in this version centers on reproducing a more “natural” pulsatile pattern of GH release — short bursts followed by a return to baseline — rather than the sustained elevation studied with the DAC version. This distinction (pulsatile vs. sustained release) is itself a research question in growth-hormone-axis physiology.

Evidence Status — Well-documented

Well-documented mechanism and pharmacokinetics.

As with the DAC version, the receptor mechanism is well understood from the broader GHRH research literature. Evidence specific to this exact fragment's pharmacokinetics in humans exists but is less extensive than for better-funded, longer-studied GH-axis compounds.

Research Use Only

This page is a scientific reference summarizing publicly available research literature. It contains no dosing, administration, or protocol guidance, and nothing here constitutes medical advice. BactoCore does not sell this or any peptide referenced in this index — the only product sold directly is bacteriostatic water. See the Safety section for who should not handle research compounds, and the Research Use Disclaimer for full terms.