Selank

Overview

Selank is a synthetic peptide analog of tuftsin, a naturally occurring immunomodulatory peptide. Like Semax, it was developed and is most extensively studied within Russian pharmacological research.

Proposed Mechanism

Modulates GABAergic tone and monoamine activity. Studies to date have not shown the sedation or dependence liability associated with benzodiazepines.

Research Context

Research on Selank centers on its anxiolytic (anxiety-reducing) properties via modulation of GABAergic tone and monoamine neurotransmitter activity — without the sedative or dependence-related mechanisms associated with benzodiazepine-class anti-anxiety medications, according to the studies conducted so far.

Evidence Status — Well-documented

Well-documented within Russian clinical literature; independent replication elsewhere is limited.

As with Semax, the evidence base is substantial within Russian clinical literature but has seen limited independent replication in Western research settings. The proposed mechanism (GABAergic modulation without benzodiazepine-like effects) is scientifically plausible and consistent with the broader pharmacology of related compounds, but independent confirmation outside the original research tradition remains limited.

Research Use Only

This page is a scientific reference summarizing publicly available research literature. It contains no dosing, administration, or protocol guidance, and nothing here constitutes medical advice. BactoCore does not sell this or any peptide referenced in this index — the only product sold directly is bacteriostatic water. See the Safety section for who should not handle research compounds, and the Research Use Disclaimer for full terms.